Before Your Appointment
Ocrevus treats both primary progressive MS (PPMS) and relapsing forms of MS. It is administered as an intravenous infusion twice a year. Prior to infusion day, your provider might have a few required tests that need to be updated and/or a current MRI. Ocrevus also offers a co-pay program that you may wish to sign up for before your first infusion. If you’re having trouble navigating the financial assistance programs, check in with your healthcare provider administering your infusion. Many healthcare providers offer financial counseling and help when enrolling into these often complex programs.
What to Bring on Infusion Day
If you’re receiving your first infusion at IVX Health, all of our private patient suites have large flat screen TVs with cable and Netflix to catch up on your favorite shows and movies. Otherwise, it’s a good idea to bring along something to pass the time – a book, laptop, etc. IVX Health also provides snacks and drinks, but if you’re choosing an alternative infusion site, you might need to pack your own. Ocrevus additionally has a handy infusion checklist you can print out for reference before infusion day. Expect for each Ocrevus infusion visit to last somewhere between 4-6 hours.
Before the Infusion Begins
Each infusion center follows a certain process when it comes to an Ocrevus infusion. As noted in the FDA’s prescribing information for Ocrevus, a nurse will typically perform a standard pre-infusion assessment or screening to ensure there are no contraindications and will typically give you a corticosteroid and an antihistamine 30-60 minutes before to help reduce potential infusion reactions. These medications may vary based on what your provider chooses.
Your First Infusion
Ocrevus is given twice a year, with the exception of the first infusion being split across two separate infusions (given two weeks apart from one another). The initial two doses last roughly 2.5 hours each. After your first rounds of Ocrevus, you will return every 6 months for a single infusion, lasting around 3.5 hours. At times, you might feel a little cold as the liquid continues running through your veins. If you’re at IVX Health, simply ask your nurse to bring you one of our cozy blankets or a heated hot/cold pack. A clinician, such as a registered nurse or nurse practitioner, will be monitoring you, including checking vital signs throughout your infusion. If you are experiencing any type of reaction, the clinicians will be readily available to treat and manage. At IVX Health, your safety is our top priority.
After your Ocrevus infusion, you will be required to stay for an observation period to ensure you don’t have any side effects or infusion reactions. Some of the possible side effects include itchy skin, hives, issues breathing, fatigue, nausea, and/or coughing. For a full list of possible reactions, please reference Ocrevus’ full reaction list. It is important to notify your healthcare provider if any of the symptoms flare up within 24 hours post infusion and are not considered mild to moderate.
Patient Support and Financial Assistance
As noted on the Ocrevus website, an Ocrevus infusion costs an estimated $65,000 annually, but the majority of patients will not pay this amount, as what you are expected to pay depends on several factors, ranging from your insurance coverage to your assistance program eligibility. The most common types of insurance available include Commercial or Private insurance, Medicare, and Medicaid. Ocrevus has detailed data on each healthcare plan’s estimated out-of-pocket cost available on their website. Additionally, you might be eligible for one of the Ocrevus assistance programs below:
- Ocrevus Co-Pay Program: This program provides direct financial assistance to MS patients to help with co-pays, out-of-pocket costs, and co-insurance. Eligible commercially insured patients can get help from a Patient Navigator to enroll in the Ocrevus Co-Pay Program.
- Independent Co-Pay Assistance Foundations: If you need additional help with co-pay, you can get it from independent co-pay financial organizations that assist patients with specific conditions. Your Patient Navigator can refer you to such a foundation including those covered by Medicaid and Medicare.
- Genentech Patient Foundation: The Genentech Patient Foundation provides free Ocrevus infusions to individuals who lack any insurance coverage or who have financial concerns. To be eligible for Genentech, insured patients must have exhausted all other types of patient assistance mentioned above.
Ocrevus additionally hosts free educational events to learn more about the different types of MS, Ocrevus in general, and to connect with others in your area living with MS.