Gamunex-C Infusion Therapy

Gamunex-C is a biologic therapy that is indicated to treat:

Gamunex-C is approved for use in several medical conditions, including:

• Primary Immunodeficiency (PI): A group of disorders where the immune system does not function properly, leading to increased susceptibility to infections.
• Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A neurological disorder characterized by progressive weakness and impaired sensory function in the limbs.
• Idiopathic Thrombocytopenic Purpura (ITP): A condition causing low platelet counts, leading to increased risk of bleeding.
• Secondary Immunodeficiency: Due to other conditions like HIV/AIDS or chemotherapy treatment.
• Kawasaki Syndrome: A disease in children that causes inflammation in blood vessels.

Referring providers also have the option to order Gamunex-C off-label, which will require additional approvals from the patient’s health plan.

Gamunex-C is a brand of immune globulin (IG), specifically human immune globulin intravenous (IGIV) with subcutaneous injection options. It contains a broad spectrum of antibodies and is used to treat various conditions where the immune system is compromised or requires support.

Gamunex-C is used to replace or supplement antibodies in patients with immune deficiencies and to modulate the immune response in certain autoimmune disorders. This can help protect against infections or reduce symptoms in autoimmune conditions.

The dosing and administration of Gamunex-C vary depending on the indication, patient weight, and individual patient response. In general:

• Primary Immunodeficiency: Doses can range from 300 mg/kg to 600 mg/kg every 3 to 4 weeks, depending on the clinical scenario.
• Chronic Inflammatory Demyelinating Polyneuropathy: Initial dose is often 2 g/kg divided over 2 to 5 days, followed by maintenance dosing every 3 to 4 weeks.
• Idiopathic Thrombocytopenic Purpura: A single dose of 1 g/kg or a divided dose of 2 g/kg over 2 days may be used.

Dosing should always be determined by a healthcare provider, taking into account individual patient characteristics and response to therapy.

Common side effects of Gamunex-C may include:

• Mild headaches
• Fatigue
• Fever
• Chills
• Joint pain
• Nausea

Rare but serious side effects can include:

• Severe allergic reactions
• Blood clots
• Kidney problems
• Aseptic meningitis
• Hemolysis

Patients should always discuss potential side effects with their healthcare provider and understand what to do in case of severe reactions.

To prepare for an infusion of Gamunex-C, patients should:

• Follow Medical Advice: Every patient should follow any specific instructions from their healthcare provider, such as fasting or hydration requirements.
• Wear Comfortable Clothing: As the infusion can take a few hours, wearing comfortable clothing helps.
• Bring Entertainment: Since the infusion process can be lengthy, bringing a book, tablet, or music can help pass the time. IVX Health also offers in-room TVs with streaming options.
• Ensure Transportation: Patients might need assistance getting home after the infusion, so arranging transportation is advisable.

IVX Health patients may also consult the FAQs and New Patient Information sections of the IVX website.

To obtain a referral for Gamunex-C treatments:

• Consult with a Healthcare Provider: A primary care physician or specialist can evaluate the need for IVIG therapy and refer to an appropriate center for treatment.
• Documentation and Tests: The referring healthcare provider may require certain tests or documentation to support the need for IVIG therapy.
• Insurance Considerations: Patients should check with their insurance provider to understand the referral process and coverage for IVIG therapy.
• Schedule an Appointment: Once the referral is obtained, patients should contact the infusion center to schedule their first appointment and discuss any pre-appointment requirements.

Patients chose IVX Health to receive their ongoing Gamunex-C treatments because:

• ALL private suites
• Comfortable recliners, with chairs for guests
• Evening & weekend appointments
• Friendly clinical staff deliver personal service
• Big screen TVs, high-speed WiFi, free snacks